Periosteal chondrosarcoma introduction periosteal (also called parosteal or juxtacortical) chondrosarcoma ( periosteal chs ) is a malignant cartilaginous neoplasm of the outer cortical surface of long bones. It is rare and it has a predilection for the male sex. Its incidence has two peaks, one in the 2 nd and the other in the 4 th decade and it is exceptional before puberty. Location it is usually located in the meta-diaphyseal areas around the knee, but also in the proximal humerus. When located in the posterior aspect of the distal femur, it must be differentiated from parosteal osteosarcoma, as will be discussed later. Clinically , it has a rather slow (14m on average) asymptomatic course, with little or no pain and/ or swelling. Imaging it presents as a rounded lucency sitting on the outer cortex and usually it contains granular or ring opacities due to calcification (“pop-corn” pattern), depending on the age of the lesion. The underlying cortex appears thickened, sclerotic, with a sharply defined border and occasionally, periosteal “spurring” at the periphery. Typically the medullary canal is uninvolved, as can be demonstrated by ct. Mri is only useful if no calcifications are present. Histology reveals lobular well differentiated cartilage, usually grade 1 or 2. In fact, the grade 1 features are in the spectrum of periosteal chondroma. Therefore, to differentiate periosteal chs from periosteal chondroma, one should take into account the following: periosteal chs has a larger size (> 5 cm. ), it occurs after puberty, it usually shows signs of grade 2-3 malignancy and the cortical erosion is more prominent, eventually with permeation and medullary canal involvement. As a result, grade 1 periosteal chs should be considered only in an adult patient with clear permeation of the cortex. It is not clear whether periosteal chs can originate from a periosteal chondroma.     prognosis and treatment local recurrences are rare if wide resection is performed and lung metastases are very rare. No chemotherapy is required.   differential diagnosis also includes periosteal osteosarcoma, high-grade surface osteosarcoma and parosteal osteosarcoma.   periosteal osteosarcoma is less malignant than classical osteosarcoma, but definitively more aggressive than periosteal chs. Contrary to periosteal chs, it can occur also in children before puberty and usually has a shorter (6m on average) clinical course with moderate pain and palpable mass. The radiography shows a lucent diaphyseal mass on the outer cortical surface. The periosteum is elevated and fusiform,.





The Izard County Animal Rescue Effort (ICARE) was first organized in March, 2003 by a group of volunteers in Melbourne, (Izard County) Arkansas, for the purpose of promoting responsible, compassionate care and relief of suffering for animals while providing low-cost spay and neuter programs to the community.  We received our non-profit 501(c)(3) status on November 19, 2003.

Since that time, we have adopted approximately 620 dogs and 108 cats and have altered 1,500 dogs and cats through our low cost spay and neuter clinics with Arkansans for Animals (AFA), a community grant, and one-on-one with our local veterinarians.

We do not have a shelter.   All our animals are cared for in foster homes throughout the county.

We do make out-of-state adoptions.

Our complete list of pets available for adoption may be seen at

ADOPTION FEES: Please note:
Unless otherwise noted in the individual animal description, the adoption fee for mixed breed dogs is $75 in the State of Arkansas and $95 out of state.  Breed and Designer Breed dog adoption fees are higher and will be noted in the individual animal description.  PAWS IN PRISON trained dogs adoption fees are $125.  Cats are $25.  Fees can be adjusted on an individual basis.  Fees may change at any time.

We meet on the second Thursday of each month at the Community Building adjacent to City Hall in Melbourne beginning at 6:30 PM, with snacks and socializing beginning at 6:00 PM.

The American Society for the Prevention of Cruelty to Animals (the “ASPCA”) is deeply honored to be able to grant to Izard County Animal Rescue Effort the amount of $2500.00. These funds are designated for the following purpose as outlined in your grant request and, if applicable, its amendments: Voucher Spay/Neuter Program for Low-Income Residents.

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Contact Us at (870) 368-5000

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